Scissor Sisters are an American alternative band formed in 2001. The members consist of vocalists Jake Shears and Ana Matronic, multi-instrumentalist Babydaddy, lead guitar/bassist, Del Marquis, and drummer Randy Real (who replaced former drummer Paddy Boom). "Spawned by the scuzzy, gay nightlife scene of New York", they took their name from a sexual position between two women also known as tribadism.

Released in 2004, their their self-titled debut album raised public awareness of the band's existence. The album gained much success in the United Kingdom – a country they call their "spiritual home" – where the album went to number one, was the best-selling album of that year and was later certified platinum by the BPI. Although merely successful in their native United States, the album was also a chart success in countries around Europe, in Australia and in Canada. Several releases from the album accomplished positions within the top-twenty of the UK Singles Chart including: "Laura", "Comfortably Numb", "Take Your Mama", "Mary" and "Filthy/Gorgeous" – the latter also went to number one on the Billboard chart for Hot Dance Club Songs. In 2006, the band released their second studio album, Ta-Dah, which proved to be a commercial and critical success and scored the band two consecutive number-one albums in UK as well producing their debut number-one single in the UK "I Don't Feel Like Dancin'". Displaying a shift towards a more club-oriented sound, their third studio album, Night Work, was released in 2010; charting at number two on the UK Albums Chart.

Scissor Sisters have collaborated with a number of other well known pop musicians including Elton John and Kylie Minogue; these particular collaborations have been received positively by both critics and other notable figures. Bono, lead vocalist of rock band U2, described Scissor Sisters as "the best pop group in the world" in 2004.